Parametric evaluation of impedance curve in radiofrequency ablation : a quantitative description of the asymmetry and dynamic variation of impedance in bovine ex vivo model

Fonseca, Ronei Delfino da; Santos, Paulo Roberto; Monteiro, Melissa Silva; Fernandes, Luciana Alves; Campos, Andreia Henrique; Borges, Dıbio L.; Rosa, Suélia de Siqueira Rodrigues Fleury

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dc.contributor.author	Fonseca, Ronei Delfino da	-
dc.contributor.author	Santos, Paulo Roberto	-
dc.contributor.author	Monteiro, Melissa Silva	-
dc.contributor.author	Fernandes, Luciana Alves	-
dc.contributor.author	Campos, Andreia Henrique	-
dc.contributor.author	Borges, Dıbio L.	-
dc.contributor.author	Rosa, Suélia de Siqueira Rodrigues Fleury	-
dc.date.accessioned	2021-05-28T15:48:01Z	-
dc.date.available	2021-05-28T15:48:01Z	-
dc.date.issued	2021-01-15	-
dc.identifier.citation	FONSECA, Ronei Delfino da et al. Parametric evaluation of impedance curve in radiofrequency ablation: a quantitative description of the asymmetry and dynamic variation of impedance in bovine ex vivo model. PLoS ONE, v. 16, n. 1, e0245145, 2021. https://doi.org/ 10.1371/journal.pone.0245145. Disponível em: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0245145. Acesso em: 28 maio 2021.	pt_BR
dc.identifier.uri	https://repositorio.unb.br/handle/10482/41060	-
dc.language.iso	Inglês	pt_BR
dc.publisher	PLoS ONE	pt_BR
dc.rights	Acesso Aberto	pt_BR
dc.title	Parametric evaluation of impedance curve in radiofrequency ablation : a quantitative description of the asymmetry and dynamic variation of impedance in bovine ex vivo model	pt_BR
dc.type	Artigo	pt_BR
dc.subject.keyword	Ablação por radiofrequência	pt_BR
dc.subject.keyword	Carcinoma hepatocelular	pt_BR
dc.rights.license	Copyright: © 2021 da Fonseca et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.	pt_BR
dc.identifier.doi	https://doi.org/ 10.1371/journal.pone.0245145	pt_BR
dc.description.abstract1	Radiofrequency ablation (RFA) is a treatment for liver tumors with advantages over the traditional treatment of surgical resection. This procedure has the shortest recovery time in early stage tumors. The objective of this study is to parameterize the impedance curve of the RFA procedure in an ex vivo model by defining seven parameters (t1/2, tminimum, tend, Zinitial, Z1/2, Zminimum and Zend). Based on these parameters, three performance indices are defined: one to identify the magnitude of impedance curve asymmetry (δ), one Drop ratio (DR) describing the percentage of impedance decrease until the minimum impedance point is reached, and Ascent Ratio (AR) describing the magnitude of increase in impedance from the minimum impedance point to its maximum point. Fifty ablations were performed in a bovine ex vivo model to measure and evaluate the proposed parameters and performance index. The results show that the groups had an average δ of 29.02%, DR of 22.41%, and AR of 545.33% for RFA without the use of saline or deionized solutions. The saline solution and deionized water-cooled groups indicated the correlation of performance indices δ, DR, and AR with the obtained final ablation volume. Therefore, by controlling these parameters and indices, lower recurrence is achieved.	pt_BR
Collection(s) :	CIC - Artigos publicados em periódicos ENM - Artigos publicados em periódicos FGA - Artigos publicados em periódicos TEC UnB - Artigos publicados em periódicos